NimbleGen MS 200 Microarray Scanner

Instrument Details

• Make : Tecan Austria GmbH
• Model : NimbleGen MS 200 [Roche]
   

Specifications :

• Pixel resolution: 2 μm, 5 μm, 10 μm, 20 μm, 40 μm
• Dynamic range: 105 (16-bit data format)
• Recommended dyes: Cy3 and Cy5 (also compatible: Alexa 555 and Alexa 647 or DY 547 and DY 647)
• Limit of detection: 0.0025 Cy3; 0.005 Cy5 (chromophores/μm2)
• Dynamic Autofocus: Auto-adjusts for optimal focus position and angle.
• Uniformity: <4% CV
• Light source: Two solid-state lasers (532 nm and 635 nm)
• Detector: Two low dark current PMT (photomultiplier tubes)
• Glass slides specifications: 25 x 75 mm (1 x 3 in)
• Ozone protection: Carbon-filtered airflow

Applications:

• Gene expression – NimbleGen microarrays enable accurate, sensitive, and specific interrogation of genome-wide expression for any sequenced and annotated genome.
• Sequence Capture – a revolutionary process for the enrichment of selected genomic regions from full complexity human genomic DNA in a single step.
• CGH/CNV – Comparative Genomic Hybridization (CGH) measures DNA copy number differences between a test and reference genome.
• ChIP-chip – Chromatin Immunoprecipitation-on-chip is a powerful tool to map chromatin structure and DNA binding sites of transcription factors and polymerases.
• DNA Methylation – NimbleGen provides the most sensitive and specific DNA Methylation microarrays on the market.
• CGS – Comparative Genome Sequencing (CGS) rapidly surveys entire microbial genomes, identifying SNPs, insertions, or deletions and then fully characterizing them by array sequencing with unrivaled speed and accuracy.

Contact Us:

• Director, ICAR-CPRI,Shimla(H.P.)-171001
• Phone: 0177-2625073
• Mobile:+91-9418046415
• Email Id: director.cpri@icar.gov.in